It's a 271 mile ride through the Virginia Appalachian Mountains connecting nine waterfalls. It might be a bit much to try and manage in a day, but over a couple of days it'd be a two nearly 300km days of twisty road riding with a lot of waterfall watching in between. If two days of mountain roads and waterfalls don't cure what ails you, nothing will.
I'd previously thought about doing a ride down the Appalachians to Deal's Gap as the full solar eclipse is passing over there in mid-August this year. This is about two thirds of the way down from Ontario. It'd make a nice break from the drive back north to spend a couple of days chasing waterfalls along winding mountain roads.